Patient treatment satisfaction after switching to NovoMix® 30 (BIAsp 30) in the IMPROVE™ study: an analysis of the influence of prior and current treatment factors
Identifieur interne : 000118 ( France/Analysis ); précédent : 000117; suivant : 000119Patient treatment satisfaction after switching to NovoMix® 30 (BIAsp 30) in the IMPROVE™ study: an analysis of the influence of prior and current treatment factors
Auteurs : Meryl Brod [États-Unis] ; Paul Valensi [France] ; Joseph A. Shaban ; Don M. Bushnell [États-Unis] ; Torsten L. Christensen [Danemark]Source :
- Quality of Life Research [ 0962-9343 ] ; 2010.
Abstract
Understanding treatment satisfaction (TS) for diabetes is increasingly important as treatment options increase. This study examines treatment satisfaction with NovoMix® 30 in an observational study in patients with type 2 diabetes.
The DiabMedSat assesses Overall, Treatment Burden, Symptom and Efficacy Treatment Satisfaction. The impact of type of pretreatment variables on TS was examined by ANOVA at baseline and week 26. Satisfaction at week 26 was examined by
The data set comprised 17,488 persons. Prior treatment with insulin had a more positive impact on baseline satisfaction. At week 26, there were no differences between type of prior treatment groups in Overall, Symptoms and Burden TS. Current treatment with NovoMix 30 significantly improved TS. Regression analyses examining the combined effect of pretreatment factors and current treatment factors found that all factors except for age-impacted TS although the domains impacted varied.
Patients treated with NovoMix 30 reported improved treatment satisfaction, and the improvement is considered clinically meaningful to patients.
Url:
DOI: 10.1007/s11136-010-9699-0
PubMed: 20602172
PubMed Central: 2963740
Affiliations:
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PMC:2963740Le document en format XML
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Shaban</name><affiliation><nlm:aff id="Aff3">Department of Medicine, Windsor Regional Hospital, Windsor, ON Canada</nlm:aff><wicri:noCountry code="subfield">ON Canada</wicri:noCountry></affiliation></author><author><name sortKey="Bushnell, Don M" sort="Bushnell, Don M" uniqKey="Bushnell D" first="Don M." last="Bushnell">Don M. Bushnell</name><affiliation wicri:level="2"><nlm:aff id="Aff4">Health Research Associates, 6505 216th Street SW, Suite 105, Mountlake Terrace, WA 98043 USA</nlm:aff><country xml:lang="fr">États-Unis</country><placeName><region type="state">Washington (État)</region></placeName><wicri:cityArea>Health Research Associates, 6505 216th Street SW, Suite 105, Mountlake Terrace</wicri:cityArea></affiliation></author><author><name sortKey="Christensen, Torsten L" sort="Christensen, Torsten L" uniqKey="Christensen T" first="Torsten L." last="Christensen">Torsten L. Christensen</name><affiliation wicri:level="1"><nlm:aff id="Aff5">Novo Nordisk A/S, Hummeltoftevej 49, 2830 Virum, Denmark</nlm:aff><country xml:lang="fr">Danemark</country><wicri:regionArea>Novo Nordisk A/S, Hummeltoftevej 49, 2830 Virum</wicri:regionArea><wicri:noRegion>2830 Virum</wicri:noRegion></affiliation></author></analytic><series><title level="j">Quality of Life Research</title><idno type="ISSN">0962-9343</idno><idno type="eISSN">1573-2649</idno><imprint><date when="2010">2010</date></imprint></series></biblStruct></sourceDesc></fileDesc><profileDesc><textClass></textClass></profileDesc></teiHeader><front><div type="abstract" xml:lang="en"><sec><title>Purpose</title><p>Understanding treatment satisfaction (TS) for diabetes is increasingly important as treatment options increase. This study examines treatment satisfaction with NovoMix<sup>®</sup> 30 in an observational study in patients with type 2 diabetes.</p></sec><sec><title>Methods</title><p>The DiabMedSat assesses Overall, Treatment Burden, Symptom and Efficacy Treatment Satisfaction. The impact of type of pretreatment variables on TS was examined by ANOVA at baseline and week 26. Satisfaction at week 26 was examined by <italic>t</italic>-test and effect size. Linear regression models examined impact of prior treatment factors (age, gender, duration of diabetes, type of prior treatment and diabetes-related comorbidities) and current treatment factors (weight gain, hypoglycemic events, reaching therapeutic goal) on TS.</p></sec><sec><title>Results</title><p>The data set comprised 17,488 persons. Prior treatment with insulin had a more positive impact on baseline satisfaction. At week 26, there were no differences between type of prior treatment groups in Overall, Symptoms and Burden TS. Current treatment with NovoMix 30 significantly improved TS. Regression analyses examining the combined effect of pretreatment factors and current treatment factors found that all factors except for age-impacted TS although the domains impacted varied.</p></sec><sec><title>Conclusions</title><p>Patients treated with NovoMix 30 reported improved treatment satisfaction, and the improvement is considered clinically meaningful to patients.</p></sec></div></front><back><div1 type="bibliography"><listBibl><biblStruct><analytic><author><name sortKey="Albrecht, G" uniqKey="Albrecht G">G Albrecht</name></author><author><name sortKey="Hoogstraten, J" uniqKey="Hoogstraten J">J Hoogstraten</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Atkinson, Mj" uniqKey="Atkinson M">MJ Atkinson</name></author><author><name sortKey="Kumar, R" uniqKey="Kumar R">R Kumar</name></author><author><name sortKey="Cappelleri, Jc" uniqKey="Cappelleri J">JC Cappelleri</name></author><author><name sortKey="Hass, Sl" uniqKey="Hass S">SL 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uniqKey="Martin M">M Martin</name></author><author><name sortKey="Eremenco, S" uniqKey="Eremenco S">S Eremenco</name></author><author><name sortKey="Mcelroy, S" uniqKey="Mcelroy S">S McElroy</name></author><author><name sortKey="Verjee Lorenz, A" uniqKey="Verjee Lorenz A">A Verjee-Lorenz</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Ring, L" uniqKey="Ring L">L Ring</name></author><author><name sortKey="Hofer, S" uniqKey="Hofer S">S Hofer</name></author><author><name sortKey="Heuston, F" uniqKey="Heuston F">F Heuston</name></author><author><name sortKey="Harris, D" uniqKey="Harris D">D Harris</name></author><author><name sortKey="O Oyle, Ca" uniqKey="O Oyle C">CA O’Boyle</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Matza, Ls" uniqKey="Matza L">LS Matza</name></author><author><name sortKey="Boye, Ks" uniqKey="Boye K">KS Boye</name></author><author><name sortKey="Yurgin, N" uniqKey="Yurgin N">N Yurgin</name></author><author><name sortKey="Brewster Jordan, J" uniqKey="Brewster Jordan J">J Brewster-Jordan</name></author><author><name sortKey="Mannix, S" uniqKey="Mannix S">S Mannix</name></author><author><name sortKey="Shorr, Jm" uniqKey="Shorr J">JM Shorr</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Valensi, P" uniqKey="Valensi P">P Valensi</name></author><author><name sortKey="Benroubi, M" uniqKey="Benroubi M">M Benroubi</name></author><author><name sortKey="Borzi, V" uniqKey="Borzi V">V Borzi</name></author><author><name sortKey="Gumprecht, J" uniqKey="Gumprecht J">J Gumprecht</name></author><author><name sortKey="Kawamori, R" uniqKey="Kawamori R">R Kawamori</name></author><author><name sortKey="Shaban, J" uniqKey="Shaban J">J Shaban</name></author></analytic></biblStruct></listBibl></div1></back></TEI><affiliations><list><country><li>Danemark</li><li>France</li><li>États-Unis</li></country><region><li>Californie</li><li>Washington (État)</li><li>Île-de-France</li></region><settlement><li>Paris</li></settlement></list><tree><noCountry><name sortKey="Shaban, Joseph A" sort="Shaban, Joseph A" uniqKey="Shaban J" first="Joseph A." last="Shaban">Joseph A. Shaban</name></noCountry><country name="États-Unis"><region name="Californie"><name sortKey="Brod, Meryl" sort="Brod, Meryl" uniqKey="Brod M" first="Meryl" last="Brod">Meryl Brod</name></region><name sortKey="Bushnell, Don M" sort="Bushnell, Don M" uniqKey="Bushnell D" first="Don M." last="Bushnell">Don M. Bushnell</name></country><country name="France"><region name="Île-de-France"><name sortKey="Valensi, Paul" sort="Valensi, Paul" uniqKey="Valensi P" first="Paul" last="Valensi">Paul Valensi</name></region></country><country name="Danemark"><noRegion><name sortKey="Christensen, Torsten L" sort="Christensen, Torsten L" uniqKey="Christensen T" first="Torsten L." last="Christensen">Torsten L. Christensen</name></noRegion></country></tree></affiliations></record>Pour manipuler ce document sous Unix (Dilib)
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